Package: dotgen 0.1.0

Xiaoran Tong

dotgen: Gene-Set Analysis via Decorrelation by Orthogonal Transformation

Decorrelates a set of summary statistics (i.e., Z-scores or P-values per SNP) via Decorrelation by Orthogonal Transformation (DOT) approach and performs gene-set analyses by combining transformed statistic values; operations are performed with algorithms that rely only on the association summary results and the linkage disequilibrium (LD). For more details on DOT and its power, see Olga (2020) <doi:10.1371/journal.pcbi.1007819>.

Authors:Olga Vsevolozhskaya [aut], Dmitri Zaykin [aut], Xiaoran Tong [aut, cre]

dotgen_0.1.0.tar.gz
dotgen_0.1.0.zip(r-4.7)dotgen_0.1.0.zip(r-4.6)dotgen_0.1.0.zip(r-4.5)
dotgen_0.1.0.tgz(r-4.6-any)dotgen_0.1.0.tgz(r-4.5-any)
dotgen_0.1.0.tar.gz(r-4.7-any)dotgen_0.1.0.tar.gz(r-4.6-any)
dotgen_0.1.0.tgz(r-4.6-emscripten)
manual.pdf |manual.html
card.svg |card.png
dotgen/json (API)

# Install 'dotgen' in R:
install.packages('dotgen', repos = c('https://xiaoran831213.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/xiaoran831213/dotgen/issues

On CRAN:

Conda:

2.32 score 21 scripts 683 downloads 9 exports 1 dependencies

Last updated from:89960cae63. Checks:7 WARNING, 2 OK. Indexed: yes.

TargetResultTimeFilesSyslog
linux-devel-x86_64WARNING111
source / vignettesOK149
linux-release-x86_64WARNING136
macos-release-arm64WARNING166
macos-oldrel-arm64WARNING145
windows-develWARNING63
windows-releaseWARNING61
windows-oldrelWARNING88
wasm-releaseOK146

Exports:cstdotdot_artdot_artadot_chisqdot_fisherdot_rtpdot_tpmzsc

Dependencies:mvtnorm