Package 'dotgen'
| Title: |
Gene-Set Analysis via Decorrelation by Orthogonal Transformation |
| Description: |
Decorrelates a set of summary statistics (i.e., Z-scores
or P-values per SNP) via Decorrelation by Orthogonal
Transformation (DOT) approach and performs gene-set analyses by
combining transformed statistic values; operations are
performed with algorithms that rely only on the association
summary results and the linkage disequilibrium (LD). For more
details on DOT and its power, see Olga (2020)
<doi:10.1371/journal.pcbi.1007819>. |
| Authors: |
Olga Vsevolozhskaya [aut]
 , Dmitri Zaykin [aut]
, Xiaoran Tong [aut,
cre] |
| Maintainer: |
Xiaoran Tong <[email protected]> |
| License: |
GPL (>= 2) |
| Version: |
0.1.0 |
| Built: |
2026-05-20 06:44:43 UTC |
| Source: |
https://github.com/xiaoran831213/dotgen |
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