Package: dotgen
Title: Gene-Set Analysis via Decorrelation by Orthogonal Transformation
Version: 0.1.0
Date: 2020-11-03
Description: Decorrelates a set of summary statistics (i.e., Z-scores
        or P-values per SNP) via Decorrelation by Orthogonal
        Transformation (DOT) approach and performs gene-set analyses by
        combining transformed statistic values; operations are
        performed with algorithms that rely only on the association
        summary results and the linkage disequilibrium (LD). For more
        details on DOT and its power, see Olga (2020)
        <doi:10.1371/journal.pcbi.1007819>.
Authors@R: c(
  person("Olga", "Vsevolozhskaya", email = "ovs222@@g.uky.edu", role = "aut",
         comment = c(ORCID = "0000-0001-9376-3645")),
  person("Dmitri", "Zaykin", email = "zaykin@@gmail.com", role = "aut",
          comment = c(ORCID = "0000-0002-9444-2859")),
  person("Xiaoran", "Tong", email = "tongxia1@msu.edu", role = c("aut", "cre"),
          comment = c(ORCID = "0000-0002-4648-3330")))
Depends: R (>= 3.5.0), mvtnorm
License: GPL (>= 2)
URL: https://github.com/xiaoran831213/dotgen
Encoding: UTF-8
Author: Olga Vsevolozhskaya [aut]
        (<https://orcid.org/0000-0001-9376-3645>), Dmitri Zaykin [aut]
        (<https://orcid.org/0000-0002-9444-2859>), Xiaoran Tong [aut,
        cre] (<https://orcid.org/0000-0002-4648-3330>)
Maintainer: Xiaoran Tong <tongxia1@msu.edu>
RoxygenNote: 7.1.1
Roxygen: list(markdown = TRUE)
Repository: https://xiaoran831213.r-universe.dev
Date/Publication: 2020-11-23 20:11:14 UTC
RemoteUrl: https://github.com/xiaoran831213/dotgen
RemoteRef: HEAD
RemoteSha: 89960cae63a0110541d2f7cee0dcb76d74b8b913
NeedsCompilation: no
Packaged: 2026-06-19 10:43:19 UTC; root